Bioequivalence Study of 1,500 mg Glucosamine Sulfate in Thai Healthy Volunteers
نویسندگان
چکیده
منابع مشابه
Bioequivalence Study of 1,500 mg Glucosamine Sulfate in Thai Healthy Volunteers
Several clinical studies have indicated that glucosamine sulphate is effective in controlling osteoarthritis (OA) symptoms and disease progression [1-4]. In particular, two randomised, placebo-controlled, double-blind trials of 3-year duration in knee osteoarthritis (OA) patients, showed that this symptom-modifying effect is sustained over long-term treatment courses [5,6]. Moreover, many studi...
متن کاملBioequivalence study of 500 mg glucosamine sulfate in Thai healthy volunteers.
BACKGROUND AND OBJECTIVE Glucosamine sulfate is widely used to relieve symptoms from osteoarthritis. The present study was conducted in order to determine pharmacokinetic and assess the in-vivo bioequivalence of two different hard capsule formulations of glucosamine sulfate when administered as equal dose of 500 mg. The two formulations contained different salt form where reference product is N...
متن کاملBioequivalence study of 30 mg pioglitazone tablets in Thai healthy volunteers.
OBJECTIVE To compare the bioequivalent parameters of 30 mg pioglitazone tablets manufactured locally (Glista) and originally (Actos). MATERIAL AND METHOD A randomized, single dose, two-treatment, two-period, two-sequence crossover study was conducted Twenty-four healthy volunteers were recruited at Siriraj Clinical Research Unit. Each subject received a 30 mg pioglitazone tablet of both formu...
متن کاملBioequivalence study of 50 mg sertraline tablets in healthy Thai volunteers.
OBJECTIVE To determine the bioavailability of 50 mg sertraline tablets between the test product (Zotaline, M&H Manufacturing Co., Ltd, Thailand) and the reference product (Zoloft, Pfizer Australia Pty Ltd, Australia). MATERIAL AND METHOD An open-labeled, single dose, 2-treatment, 2-period, 2-sequence, randomized crossover study under fasting conditions with 14 days washout period was conducte...
متن کاملAn open-label, randomized, cross-over bioequivalence study of montelukast 10 mg tablets in healthy Thai volunteers
To determine bioequivalence of a generic 10 mg montelukast tablet formulation. A 2-period, 2sequence crossover study was designed. It included 28 healthy subjects, each subject received a single dose of the randomly assigned formulation with 240 ml water after 10-hr fasting, and 14 blood samples (6 mL each) were drawn at predose, and 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 7, 10, 12 and 24 hr pos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2012
ISSN: 0975-0851
DOI: 10.4172/jbb.10000119